Too much testosterone kills brain cells - Sep 27, 2006

The cells die via a process called apoptosis:
"WASHINGTON (Reuters) - Too much testosterone can kill brain cells, researchers say, in a finding that may help explain why steroid abuse can cause behavior changes such as aggressiveness and suicidal tendencies.

Tests on brain cells in lab dishes showed that while a little of the male hormone is good, too much of it causes cells to self-destruct in a process similar to that seen in brain illnesses such as Alzheimer's.

'Too little testosterone is bad, too much is bad but the right amount is perfect,' said Barbara Ehrlich of Yale University in Connecticut, who led the study."

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